Development and progress in spinal surgery have always been characterized by “back-and-forth movements” in clinical applications of technical innovations. Most evolutionary technical improvements which seemed to have a logical indication spectrum, with adequate feasibility and a perspective to improve early or late outcomes, have sooner or later become “standard” with a worldwide market penetration. A good example of such a development is anterior cervical discectomy and fusion (ACDF). It all started with the Cloward and Smith-Robinson technique , which was improved with the development of plates to support and fix the bone grafts. The bone grafts were replaced by cages made from different materials, and further technical improvement has led to the use of cages as stand-alone devices recently. This is a typical simple example of a continuous evolution of a surgical technique.

The lesson we can learn from this is that if a technical improvement follows the needs of the surgeon and if it improves or standardizes a surgical technique and its outcomes, the acceptance among the surgical community will be logical and high.

脊柱外科的發(fā)展和進(jìn)步總是以技術(shù)創(chuàng)新在臨床應(yīng)用中的“來(lái)回運(yùn)動(dòng)”為特征的。大多數(shù)有變革性的手術(shù)技術(shù)發(fā)展中似乎都有一個(gè)合理的指征范圍，具有可行性高且可改善早期和晚期效果的前景，遲早它們會(huì)成為滲透全球市場(chǎng)的“標(biāo)準(zhǔn)”。前路頸椎間盤(pán)切除融合術(shù)（ACDF）是詮釋這種發(fā)展歷程的一個(gè)好例子。這一切都始于Cloward和Smith-Robinson技術(shù)，隨著支持和固定移植骨鋼板的發(fā)展，該技術(shù)得到了改進(jìn)。骨移植被不同材料制成的cage取代，技術(shù)的進(jìn)一步改進(jìn)可實(shí)現(xiàn)cage作為獨(dú)立的設(shè)備使用。這是一個(gè)典型且簡(jiǎn)單例子闡釋了外科技術(shù)將不斷發(fā)展的特性。

我們從中可以學(xué)到的是，如果一項(xiàng)技術(shù)的發(fā)展是緊隨外科醫(yī)生的需求，且這發(fā)展改進(jìn)或標(biāo)準(zhǔn)化一項(xiàng)技術(shù)及其結(jié)果，那么外科界的接受度將會(huì)很高。

Part 1: From Complete Laminectomy to Microsurgical/Microendoscopic Techniques

第一部分：從全椎板切除術(shù)到顯微外科/顯微內(nèi)窺鏡技術(shù)

The history of lumbar discectomy and lumbar decompression is one of the most fascinating chapters of spine surgery which has taught us a number of important lessons.

It was in 1909 when Krause and Oppenheim described the first lumbar discectomy (Figure 1). Erroneously they described the herniated disc as a chondroma of the lumbar spinal canal. Only 2 years later Goldthwaite and Middleton were the first to describe a herniated nucleus pulposus as a reason of low back pain and sciatica (Figure 2)

腰椎間盤(pán)切除術(shù)和腰椎減壓術(shù)的歷史是脊柱外科發(fā)展中最精彩的篇章之一，它給我們帶來(lái)許多重要的啟示。

1909年，Krause和Oppenheim首次報(bào)道了腰椎間盤(pán)切除術(shù)（圖1）。他們錯(cuò)誤地將椎間盤(pán)突出描述為腰椎管內(nèi)的軟骨瘤。僅僅2年后，Goldthwaite和Middleton首次將髓核突出描述為腰痛和坐骨神經(jīng)痛的原因（圖2）。

Figure 1: F Krause and H Oppenheim: first surgical removal of a “chondroma” of the spinal canal 1909.

圖1：F Krause和H Oppenheim：1909年首次手術(shù)切除椎管內(nèi)的“軟骨瘤”。

Figure 2: JE Goldthwaite: first description of herniated nucleus pulposus as reason for sciatica, 1911.

圖2 ：JE Goldthwaite：1911年首次描述髓核突出是坐骨神經(jīng)痛的原因。

And it took another 11 years until Adson came up with the first report about surgical removal of herniated nucleus pulposus (Figure 3).

又過(guò)了11年，Adson提出了第一篇關(guān)于手術(shù)切除突出髓核的報(bào)告（圖3）。

Figure 3: AW Adson: first description of surgical removal of herniated nucleus pulposus, 1922.

圖3 AW Adson：1922年首次報(bào)道手術(shù)切除突出髓核。

However, like very often in medical history the merits for the first disc surgeries went to two other colleagues, namely, Mixter and Barr, who still are considered as having been the “first disc surgeons” in 1934 (Figure 4). They actually published the first series of successful disc operations in 1934. Their technique however was a complete laminectomy and some of the disc herniations were removed through a transdural approach.

當(dāng)然，就像醫(yī)學(xué)史上經(jīng)常發(fā)生那樣，第一例椎間盤(pán)手術(shù)的功勞歸于另外兩位醫(yī)生，即Mixter和Barr，他們?nèi)员徽J(rèn)為是1934年進(jìn)行“第一例椎間盤(pán)手術(shù)的外科醫(yī)生”（圖4）。實(shí)際上，他們?cè)?934年報(bào)道了第一批成功的椎間盤(pán)手術(shù)系列，但他們是進(jìn)行全椎板切除術(shù)，并且部分椎間盤(pán)突出是經(jīng)硬膜入路切除的。

Figure 4: WJ Mixter: first case series of surgical removal of herniated discs 1934.

圖4：WJ Mixter：1934年第一批椎間盤(pán)切除手術(shù)系列

It was obvious from the beginning that this was a very traumatic approach with the potential of a variety of complications including dural leaks and segmental instability as well as disabling back pain.

The search for less damaging approaches had started. Only 5 years later, Love described the first interlaminar approach which became the standard procedure for many years (Figure 5). But even though the rate of major surgical complications dropped over time, the problem of postoperative back pain and rapid progression of disc degeneration due to aggressive disc removal affected the clinical outcomes.

從一開(kāi)始就很明顯，這是一種非常具有創(chuàng)傷性的手術(shù)入路，有可能出現(xiàn)各種并發(fā)癥，如硬腦膜滲漏、節(jié)段性不穩(wěn)以及傷殘性背痛。

人們開(kāi)始尋找侵入性較小的手術(shù)入路。僅僅5年后，Love報(bào)道了首次經(jīng)椎板間入路，這成為多年來(lái)的標(biāo)準(zhǔn)術(shù)式（圖5）。但是，盡管主要手術(shù)并發(fā)癥的發(fā)生率隨著時(shí)間的推移而下降，但術(shù)后背痛和因激進(jìn)的椎間盤(pán)切除而導(dǎo)致椎間盤(pán)退變迅速的問(wèn)題影響了臨床結(jié)果。

Figure 5: JG Love: first description of interlaminar approach, 1939.

圖5：JG Love：1939年首次報(bào)道了經(jīng)椎板間入路

While surgery led to a significant improvement of nerve root compression signs, patient satisfaction was impaired by symptoms which were due to the collateral damage the surgeon had produced. Interestingly this fear is still immanent in today's public opinion about disc surgery.

The reduction of collateral damage was the driving force for the two pioneers of lumbar microsurgery. In the same year 1977 Yasargil and Caspar described independently a microsurgical interlaminar approach , Figures 6(a) and 6(b). One year later, it was “Tex” Williams who was the first surgeon to perform this approach in the US. The pioneering work of JA McCulloch made this approach popular in the 90s of the last century and it has become a “gold standard” at least in the neurosurgical community worldwide. Other approaches such as the lateral extraforaminal access have been described in this book as well.

雖然手術(shù)明顯的改善了神經(jīng)根受壓癥狀，但由于外科醫(yī)生造成的附帶損傷，病人的滿(mǎn)意度受到了影響。有趣的是，這種恐懼在今天關(guān)于椎間盤(pán)手術(shù)的公眾輿論中仍然存在。

減少附帶損傷是兩位腰椎顯微外科先驅(qū)者的動(dòng)力。同年1977年Yasargil和Caspar獨(dú)立地描述了顯微外科椎間板入路，圖6（a）和6（b）。一年后，"Tex " Williams成為美國(guó)首次采用上述入路的外科醫(yī)生。JA McCulloch的開(kāi)創(chuàng)性工作使這種入路在上世紀(jì)90年代流行起來(lái)，至少在全球神經(jīng)外科界，它已成為 "黃金標(biāo)準(zhǔn)"。他寫(xiě)的這本書(shū)還介紹了其他入路，如外側(cè)椎間孔外入路。

(a)

(b)

Figure 6 :  (a) G Yasargil, (b) W Caspar: first description of microsurgical interlaminar approach.

圖6 (a) G Yasargil, (b) W Caspar: 首次描述顯微外科椎板間入路。

“Microendoscopic discectomy” was described in the beginning of this century as a modification of the microsurgical technique where the surgical microscope is replaced by “open” endoscopy. This technique however did not add any further technical or clinical advantages. However both minimally invasive techniques are practiced with good and reproducible clinical outcomes.

本世紀(jì)初，“顯微內(nèi)窺鏡椎間盤(pán)切除術(shù)”被描述為顯微外科技術(shù)的改進(jìn)，手術(shù)顯微鏡被“開(kāi)放式”內(nèi)窺鏡取代。然而，這種技術(shù)并沒(méi)有增加任何進(jìn)一步的技術(shù)或臨床優(yōu)勢(shì)。但是，這兩種微創(chuàng)技術(shù)在實(shí)踐中獲得良好且可重復(fù)性的臨床效果。

 Lessons Learnt from Microsurgical Techniques

從顯微外科技術(shù)中學(xué)到的經(jīng)驗(yàn)教訓(xùn)

In summary lumbar microsurgery has significantly improved clinical short-term outcomes of lumbar discectomy mainly by reducing iatrogenic collateral damage. Thus, hospitalization times have become shorter, postop pain levels are lower, and intraoperative blood loss as well as the risk of infection is less.

Even though the advantages are obvious, several lessons had to be learnt by the protagonists of such techniques.

Since there is obviously no effect on the long-term outcome of lumbar discectomy, the acceptance especially by the older generation of spine surgeons has been low despite the obvious advantages.

It has been known for many years that long-term outcome of lumbar discectomy has different predictors than the short-term outcome. This is due to the fact that there is a progressive degeneration of the spine which can cause clinical symptoms at other levels which are not related to a previous disc surgery.

However we have learnt that one of the strongest predictors of a good long-term outcome is a good short-term outcome. And we have also learnt that a good short-term outcome is predicted by 2 factors: (1) the efficacy of nerve root compression and (2) the extent of iatrogenic collateral damage to muscles, ligaments, facet joints, nerve, and epidural space.

綜上所述，腰椎顯微手術(shù)主要通過(guò)減少醫(yī)源性附帶損傷而顯著改善了腰椎間盤(pán)切除術(shù)的臨床短期療效。術(shù)后住院時(shí)間縮短，術(shù)后疼痛程度降低，術(shù)中出血量以及感染的風(fēng)險(xiǎn)也降低。

盡管這種技術(shù)的優(yōu)勢(shì)是顯而易見(jiàn)的，但操作這些技術(shù)的主角們必須從中吸取一些經(jīng)驗(yàn)教訓(xùn)。

由于腰椎間盤(pán)切除術(shù)的長(zhǎng)期療效沒(méi)有明顯改進(jìn)，盡管有明顯的優(yōu)勢(shì)，但脊柱外科醫(yī)生，特別是老一代的，對(duì)此技術(shù)的接受程度很低。

眾所周知，腰椎間盤(pán)切除術(shù)的長(zhǎng)期療效與短期療效的預(yù)測(cè)因素不同。這是由于脊柱的進(jìn)行性退變會(huì)導(dǎo)致其他水平的臨床癥狀出現(xiàn)，而這些癥狀與之前的椎間盤(pán)切除手術(shù)無(wú)關(guān)。

但是，我們了解到，良好的短期療效是預(yù)測(cè)長(zhǎng)期療效的最有力因素之一。我們還了解到，良好的短期療效是取決于兩個(gè)因素：(1)神經(jīng)根壓迫的效果；(2)醫(yī)源性側(cè)支對(duì)肌肉、韌帶、關(guān)節(jié)突、神經(jīng)和硬膜外間隙的損傷程度。

Part 2: The “Parallel World” of “Percutaneous” and Endoscopic Techniques

第二部分：“經(jīng)皮”與內(nèi)窺鏡技術(shù)的“平行世界”

It was in 1964 when Lyman Smith published a paper about enzymatic dissolution of the nucleus pulposus, a procedure which he called chemonucleolysis. It was known at that time that an enzyme called Chymopapain, which was derived from the papaya plant, was able to hydrolyze proteoglycans. During experimental work in the 50s of the last century about the effects of papain, there was an interesting incidental finding. Intravenous injection of papain in rabbits resulted in a reversible collapse of rabbit ears, a finding which suggested an effect of this enzyme on cartilage. Similar effects were then reported on cartilage of joints, trachea, larynx, and bronchi. Since further studies on rabbits had shown that this enzyme dissolves the nucleus pulposus, it was Lyman Smith’s idea that an application in contained disc herniations could lead to an “intradiscal decompression”, thus relieving the symptoms from nerve compression due to a bulging lumbar disc.

In the 1980s this procedure became popular as the least invasive technique to treat herniated lumbar discs.

Mid- to long-term outcomes were good, complications were rare, and chemonucleolysis seemed to become a viable alternative to surgical discectomy.

Then something happened which was more a psychological phenomenon than rational based medical evolution. In the 70s, Hijikata, a Japanese surgeon, was fascinated by the posterolateral access to the disc space which was, at that time, in the pre-CT and pre-MRI era, very popular to perform diagnostic discographies (Figure 7). He developed tubes through which he could introduce this approach down to the posterolateral annulus under fluoroscopic control. With special trephines he could perforate the annulus and, using pituitary rongeurs, he could perform what he called “percutaneous nucleotomy”. He published this procedure in a regional scientific journal in Japanese language. This was one of the reasons why this procedure did not gain widespread attention among the surgical community but it was the birth of “percutaneous” and, later, endoscopic discectomy.

1964年，Lyman Smith發(fā)表了一篇關(guān)于酶溶解髓核的論文，他把這個(gè)過(guò)程稱(chēng)為化學(xué)核溶解。當(dāng)時(shí)人們知道一種名為木瓜凝乳蛋白酶的酶（Chymopapain），這種酶是從木瓜植物中提取的，能夠水解蛋白聚糖。在上世紀(jì)50年代關(guān)于木瓜蛋白酶作用的實(shí)驗(yàn)中，有一個(gè)有趣的意外發(fā)現(xiàn)。在兔子身上靜脈注射木瓜蛋白酶會(huì)引起兔子耳朵的可逆性塌陷，這一發(fā)現(xiàn)表明這種酶對(duì)軟骨是有影響。對(duì)關(guān)節(jié)、氣管、喉和支氣管的軟骨也有類(lèi)似的影響。由于對(duì)兔子的進(jìn)一步研究表明這種酶可以溶解髓核，Lyman Smith的想法是，在椎間盤(pán)突出的地方應(yīng)用這種酶可實(shí)現(xiàn)“椎間盤(pán)內(nèi)減壓”，從而緩解由于腰椎間盤(pán)突出引起的神經(jīng)壓迫癥狀。

在20世紀(jì)80年代，這種方法作為治療腰椎間盤(pán)突出癥中損傷最小的技術(shù)而流行起來(lái)。

中期、長(zhǎng)期療效良好且并發(fā)癥少，化學(xué)髓核溶解術(shù)似乎成為一個(gè)可替代椎間盤(pán)切除術(shù)的選擇。

隨后發(fā)生的事情，更多的是一種外科醫(yī)師對(duì)手術(shù)技能的執(zhí)著，而不是基于理性的醫(yī)學(xué)演變。在70年代，日本外科醫(yī)生Hijikata對(duì)通過(guò)后外側(cè)入路進(jìn)入椎間盤(pán)間隙非常著迷，當(dāng)時(shí)，在CT 和MRI之前的年代，這是非常流行的診斷椎間盤(pán)造影（圖7）。他研發(fā)了一些管子，在透視下，他可以通過(guò)這種入路進(jìn)入后外側(cè)環(huán)。使用特殊的環(huán)鉆在椎環(huán)上打孔，并用垂體咬骨鉗，他可進(jìn)行他所謂的“經(jīng)皮髓核切除術(shù)”。他在一家地區(qū)性科學(xué)雜志上用日語(yǔ)發(fā)表了這一手術(shù)過(guò)程。這也是這種手術(shù)沒(méi)有在外科界獲得廣泛關(guān)注的原因之一，但它是“經(jīng)皮”以及后來(lái)的內(nèi)窺鏡椎間盤(pán)切除術(shù)誕生的開(kāi)始。

Figure 7: Hijikata: first percutaneous nucleotomy, 1975.

圖7 Hijikata：1975年第一次進(jìn)行經(jīng)皮髓核切除術(shù)。

It was the great merit of Parviz Kambin a Philadelphian spine surgeon to further develop this procedure in the 1980s  (Figure 8).

Parviz Kambin是費(fèi)城的一位脊柱外科醫(yī)生，他在20世紀(jì)80年代進(jìn)一步發(fā)展了這一手術(shù)操作，這是他的一大功績(jī)（圖8）。

Figure 8: P Kambin: percutaneous discectomy, 1986.

圖8 P Kambin：1986年進(jìn)行經(jīng)皮椎間盤(pán)切除術(shù)。

It is the “Kambin triangle” (the safe corridor to the lumbar disc between the exiting nerve root and the superior facet) which reminds us of his pioneering work (Figure 9).

這是“Kambin三角”（出口神經(jīng)根和上小關(guān)節(jié)之間可直入腰椎間盤(pán)的安全走廊），這讓我們想起他所做過(guò)的開(kāi)創(chuàng)性工作（圖9）。

Figure 9: Kambin’s triangle for a safe posterolateral approach.

圖9：安全后外側(cè)入路的Kambin三角。

Schreiber, Suezawa, and Leu were the first to have the idea to perform this percutaneous nucleotomy under visual control using and endoscope (discoscopy) .

The author of this review adopted this technique, refined the instrument set  (Figure 10), and published the results of a randomized controlled trial comparing microdiscectomy with endoscopic posterolateral discectomy.

Schreiber、Suezawa和Leu是最先有這個(gè)想法的人，他們提出在可視控制和內(nèi)窺鏡（椎間盤(pán)鏡）下進(jìn)行經(jīng)皮髓核切除術(shù)。

這篇綜述的作者采用了這一技術(shù)，改進(jìn)了器械組（圖10），并發(fā)表了一項(xiàng)比較顯微椎間盤(pán)切除術(shù)與內(nèi)窺鏡后外側(cè)入路椎間盤(pán)切除術(shù)的隨機(jī)對(duì)照試驗(yàn)結(jié)果。

Figure 10: Early Instrument set for percutaneous endoscopic discectomy.

圖10：經(jīng)皮內(nèi)窺鏡椎間盤(pán)切除術(shù)的早期器械組。

A more lateral access route was described by Hal Mathews and Tony Yeung in the second half of the 1990s.

This lateral extraforaminal approach enabled the removal of far lateral disc herniations as well as more medially located pathologies because the approach corridor was more parallel to the posterior rim of the annulus (Figure 11).

20世紀(jì)90年代后半期，Hal Mathews和Tony Yeung描述了一種更橫向的通道。

外側(cè)椎間孔外入路可以切除遠(yuǎn)外側(cè)的椎間盤(pán)突出以及更內(nèi)側(cè)的病變，因?yàn)榇巳肼吠ǖ栏叫杏谧甸g盤(pán)環(huán)的后緣（圖11）。

Figure11: Approach corridor and visual field for transforaminal approach.

圖11：經(jīng)椎間孔入路的通道和可視范圍。

Lessons Learnt

經(jīng)驗(yàn)學(xué)習(xí)

The indication spectrum for posterolateral and transforaminal endoscopic techniques was limited, which was one of the reasons why endoscopic discectomy remained at a low level of acceptance among spine surgeons in the 1980s and 1990s.

There were other reasons: the variety of instruments was limited, the optical systems were not as good as nowadays, and the technical advantages as compared to microsurgery were small.

后外側(cè)和經(jīng)椎間孔內(nèi)窺鏡技術(shù)的指征范圍是有限的，這是80年代和90年代內(nèi)窺鏡下椎間盤(pán)切除術(shù)在脊柱外科醫(yī)生中接受程度低的原因之一。

其他原因還有：手術(shù)器械種類(lèi)有限，光學(xué)系統(tǒng)不如現(xiàn)在好，與顯微外科手術(shù)相比，技術(shù)優(yōu)勢(shì)不大。

Part 3: From a Nondisruptive to a Disruptive Surgical Technology

第三部分：從非顛覆性到顛覆性的外科技術(shù)

But what was the missing link or major step? The answer is simple: endoscopy was used in a “dry” environment because the technical advantages of joint arthroscopy were not applied.

Whereas in joint arthroscopy surgical dissection was performed “under water” with continuous irrigation and suction, this principle was not applied in the spine because of the erroneous assumption that irrigation might not be of help or necessary in non-preformed anatomic spaces. The advantages of continuous irrigation (hemostasis, flushing of small bleeding, identification of the bleeding source, better identification of microanatomy, and separation of tissue layers by simple irrigation) were not realized.

Moreover, the technique focused on lateral extraforaminal approaches, and the most traditional interlaminar approach was believed not to be feasible with such a technique.

This is why “the first wave” of lumbar endoscopic techniques remained a nondisruptive technology.

Things changed in the late 90s. It was the merit of Anthony Yeung who started to consequently apply arthroscopic technology for transforaminal as well as interlaminar approaches (Figure 12).

但這當(dāng)中是缺少了什么環(huán)節(jié)或主要步驟？答案很簡(jiǎn)單：因?yàn)殛P(guān)節(jié)鏡的技術(shù)優(yōu)勢(shì)沒(méi)有被應(yīng)用，內(nèi)窺鏡是在一個(gè)“干燥”的環(huán)境中使用的。

關(guān)節(jié)鏡手術(shù)是在“水下”通過(guò)持續(xù)沖洗和抽吸進(jìn)行的，而這一原理并沒(méi)有應(yīng)用于脊柱手術(shù)中，因?yàn)槿藗冨e(cuò)誤地認(rèn)為沖洗在非預(yù)制的解剖空間里可能沒(méi)有幫助也沒(méi)必要。連續(xù)沖洗的優(yōu)點(diǎn)（止血、沖洗少量出血、識(shí)別出血源、更好地識(shí)別微觀(guān)解剖結(jié)構(gòu)、通過(guò)簡(jiǎn)單沖洗分離組織層）均無(wú)實(shí)現(xiàn)。

此外，該技術(shù)傾向于外側(cè)椎間孔外入路，而最傳統(tǒng)的經(jīng)椎板間入路被認(rèn)為在內(nèi)窺鏡下是不可操作的。

這就是為什么腰椎內(nèi)窺鏡技術(shù)的“第一波浪潮”仍然是一種非顛覆性的技術(shù)。

在90年代末，事情開(kāi)始發(fā)生轉(zhuǎn)變。這是Anthony Yeung的功勞，他逐漸將關(guān)節(jié)鏡技術(shù)應(yīng)用于經(jīng)椎間孔以及經(jīng)椎間板入路（圖12）。

Figure 12: A Yeung: first application of transforaminal approach under continuous irrigation.

圖12：A Yeung:持續(xù)灌洗下經(jīng)椎間孔入路的首次應(yīng)用

There were three major steps, which transferred spinal endoscopy into a disruptive technology:

(1) “under-water-dissection”: continuous irrigation reduced intra- and postop bleeding and infection rates and significantly improved visibility of anatomic structures;

(2) the range of approaches increased from pure transforaminal or posterolateral to interlaminar because

(3) rongeurs, high-speed drills, and other instruments could be used.

Success rates increased and recurrence rates decreased. Rapidly this technology was adopted mainly in Asian countries.

At the beginning of the 2000s it was Sebastian Rütten, a German spine surgeon, who adopted this technology and applied it for interlaminar endoscopic approaches. This significantly enlarged the indication spectrum of this technology (Figure 13).

將脊柱內(nèi)鏡技術(shù)轉(zhuǎn)變?yōu)橐豁?xiàng)顛覆性技術(shù)的主要步驟有三個(gè)：

(1)“水下解剖”：持續(xù)沖洗減少了術(shù)中和術(shù)后的出血及感染率，并大大提高了解剖結(jié)構(gòu)的可見(jiàn)度；

(2)手術(shù)入路范圍從單純的經(jīng)椎間孔或后外側(cè)擴(kuò)大至經(jīng)椎間板；因?yàn)?/p>

(3) 可以使用骨鉗、高速磨鉆和其他器械。

成功率提高，復(fù)發(fā)率降低。這項(xiàng)技術(shù)很快被采用，特別是在亞洲國(guó)家。

在21世紀(jì)初，德國(guó)脊柱外科醫(yī)生Sebastian Rütten采用了這項(xiàng)技術(shù)，并將其應(yīng)用于經(jīng)椎板間內(nèi)窺鏡手術(shù)。這極大地?cái)U(kuò)大了這項(xiàng)技術(shù)的適應(yīng)癥范圍（圖13）。

Figure 13: S Rütten: first interlaminar approach and application of arthroscopic technique.

圖13  S Rütten：首次經(jīng)椎板間入路和應(yīng)用關(guān)節(jié)鏡技術(shù)

The current indication spectrum for thoracic and lumbar applications is wide and covers all types of degenerative (and other) pathologies which have been a domain of microsurgical techniques in the past (Table 1)

目前胸腰椎應(yīng)用的適應(yīng)癥范圍很廣，涵蓋了所有類(lèi)型的退行性（和其他）病理（表1），在過(guò)去這些是屬于顯微外科技術(shù)領(lǐng)域的。

Table 1

Indications for full-endoscopic posterior/lateral thoracic and lumbar spine surgery.

(i) Decompression of central and   foraminal spinal stenosis

(ii) Decompression of lateral recess   stenosis 

(iii) Removal of all types of disc   herniations incl. difficult cases and recurrent disc herniations 

       (a) Medial disc herniations 

??(b) Down migrated disc herniations

??(c) Bilateral disc herniations

??(d) Recurrent disc herniations 

??(e) Calcified disc herniations 

(iv) Removal of synovial cysts

(v) Removal of epidural hematoma

(vi) Removal of thoracic disc herniations   and decompression of thoracic stenosis 

(vii) Palliative decompression metastases  

表1

全內(nèi)窺鏡下胸腰椎后/側(cè)入路手術(shù)的適應(yīng)癥。

(i) 中央和椎間孔椎管狹窄減壓

(ii) 側(cè)隱窩狹窄減壓

(iii) 切除所有類(lèi)型的椎間盤(pán)突出，包括復(fù)雜病例和復(fù)發(fā)性椎間盤(pán)突出癥

??(a) 內(nèi)側(cè)椎間盤(pán)突出癥

??(b) 下移的椎間盤(pán)突出癥

??(c) 雙側(cè)椎間盤(pán)突出癥

??(d) 復(fù)發(fā)性椎間盤(pán)突出癥

??(e) 鈣化椎間盤(pán)突出癥

(iv) 切除滑膜囊腫

(v) 清除硬膜外血腫

(vi) 胸椎間盤(pán)突出癥摘除和胸椎管狹窄癥減壓

(vii) 轉(zhuǎn)移瘤的姑息性減壓

The first attempts of endoscopic lumbar spine surgery date back to the early 1980s. However, only in the last decade this technology has become a disruptive technology with the potential to replace microsurgical techniques especially for degenerative lumbar spine disorders.

The strong input and high acceptance among Asian spine surgeons have triggered a very dynamic clinical and scientific workflow on this topic. A PubMed search for scientific publications on endoscopic lumbar spine surgery shows that more than 80% of the publications have their origin in Asian countries. It has been shown that even though there is a certain learning curve for endoscopic techniques, once the surgeon is familiar with it, he can achieve comparable and sometimes better clinical results as conventional microsurgical operations.

The complication rates of experienced and well-trained surgeons are low.

The iatrogenic collateral damage of the different approaches to the lumbar spine is diminished and most of the procedures can be performed in an outpatient setting.

腰椎內(nèi)窺鏡手術(shù)的首次嘗試可以追溯到20世紀(jì)80年代初。但直到最近十年，這項(xiàng)技術(shù)才成為一項(xiàng)顛覆性的技術(shù)，才有可能取代顯微外科技術(shù)，特別是對(duì)退行性腰椎疾病。

亞洲脊柱外科醫(yī)生的激情投入和高度接受，引發(fā)了關(guān)于這一主題的非常活躍的臨床和科學(xué)工作潮。在PubMed上搜索有關(guān)腰椎內(nèi)窺鏡手術(shù)的科學(xué)出版物，發(fā)現(xiàn)80%以上的出版物都來(lái)自于亞洲國(guó)家。事實(shí)證明，盡管內(nèi)窺鏡技術(shù)有一定的學(xué)習(xí)曲線(xiàn)，但一旦外科醫(yī)生熟悉了它，他就可以取得與傳統(tǒng)顯微外科手術(shù)相當(dāng)?shù)呐R床效果，有時(shí)甚至更好。

經(jīng)驗(yàn)豐富、訓(xùn)練有素的外科醫(yī)生手術(shù)的并發(fā)癥率很低。

不同入路下進(jìn)行的腰椎手術(shù)醫(yī)源性附帶損傷減少，且大多數(shù)手術(shù)可以在門(mén)診環(huán)境進(jìn)行。

Today we are in a stage which I would call “microendoscopic blending” where the dynamics of technical improvement of endoscopic techniques suggests that the overlap of indications for this technology vs. microsurgery will step by step convert into a scenario where endoscopic techniques replace microsurgical techniques. The great challenge is the learning curve and the training of young surgeons. The acceptance of this technology is high among young surgeons but it is the task and duty of the protagonists of the older generation, the hospitals, and the scientific societies to develop learning- and training-concepts to shorten learning curves and to improve technical quality and clinical outcomes.

今天，我們正處于一個(gè)我稱(chēng)之為“顯微內(nèi)窺鏡融合”的階段，內(nèi)窺鏡技術(shù)的發(fā)展動(dòng)態(tài)表明，這種技術(shù)與顯微外科手術(shù)的適應(yīng)癥重疊將逐步轉(zhuǎn)變?yōu)閮?nèi)窺鏡技術(shù)取代顯微外科技術(shù)的局面。最大的挑戰(zhàn)是學(xué)習(xí)曲線(xiàn)和對(duì)年輕外科醫(yī)生的培訓(xùn)。年輕的外科醫(yī)生對(duì)這項(xiàng)技術(shù)的接受程度很高，所以老一代的外科醫(yī)生、醫(yī)院和科學(xué)學(xué)會(huì)的任務(wù)和職責(zé)是發(fā)展學(xué)習(xí)和培訓(xùn)概念，以縮短學(xué)習(xí)曲線(xiàn)，提高技術(shù)質(zhì)量和臨床療效。